3-Sulfosuccinimid-1-yl acetate

3-Sulfosuccinimid-1-yl acetate - Names and Identifiers

Name	3-Sulfosuccinimid-1-yl acetate
Synonyms	Ac-Sulfo-NHS Sulfo-nhs-acetate Sulfosuccinimidyl-acetate Sulfosuccinimidyl acetate N-SulfosucciniMidyl acetate 3-Sulfosuccinimid-1-yl acetate 1-Acetoxy-2,5-dioxopyrrolidine-3-sulfonic acid 1-Acetyloxy-2,5-dioxopyrrolidine-3-sulfonic acid 1-(acetyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid 1-(Acetyloxy)-2,5-dioxo-3-pyrrolidinesulfonic acid 3-Pyrrolidinesulfonic acid, 1-(acetyloxy)-2,5-dioxo-
CAS	152305-87-8
InChI	InChI=1/C6H7NO7S/c1-3(8)14-7-5(9)2-4(6(7)10)15(11,12)13/h4H,2H2,1H3,(H,11,12,13)

3-Sulfosuccinimid-1-yl acetate - Physico-chemical Properties

Molecular Formula	C6H7NO7S
Molar Mass	237.19
Density	1.80±0.1 g/cm3(Predicted)
pKa	-0.04±0.20(Predicted)
Storage Condition	2-8°C
Refractive Index	1.583

3-Sulfosuccinimid-1-yl acetate - Introduction

3-sulfoduccinimid-1-yl acetate, also known as EDPTS, is an organic compound. The following is a description of some of the properties, uses, methods and safety information about EDPTS:

Nature:
-Appearance: EDPTS are white crystalline solids.
-Solubility: EDPTS has low solubility in water, but good solubility in organic solvents.
-Melting point: The melting point of EDPTS is about 144-145 degrees Celsius.

Use:
- EDPTS are commonly used as protecting groups in organic synthesis to protect functional groups such as alcohols and amines from undesirable reactions.
- EDPTS can also be used as a complexing agent for metal ions, such as silver ions.

Method:
The preparation of-EDPTS first requires the obtaining of 2,5-dioxopyrrolidine -3-sulfonic acid (DPTS), an intermediate compound. Then, under the reaction conditions of acetic anhydride and alkali, DPTS is esterified with ethanol to obtain the final product EDPTS.

Safety Information:
- EDPTS dust may be irritating to the eyes, skin and respiratory tract, so care should be taken to avoid contact.
-Wear suitable personal protective equipment such as gloves, goggles and respirators during use.
-in storage and use should be away from the fire and high temperature environment.
-Do not store EDPTS with oxidants, acids or strong bases to avoid chemical reactions.

Please note that the nature, use, preparation and safety information mentioned here are only general descriptions of EDPTS, and specific experimental operations should be carried out according to specific conditions, and strictly follow the laboratory safety regulations.

Last Update：2024-04-09 19:05:46